منابع مشابه
Molecular epidemiology of lung cancer.
Lung cancer occurs through a complex multistage process that results from the combination of carcinogen exposure and genetic susceptibilities. The primary etiology of lung cancer is tobacco smoking, but an understanding of why some smokers develop lung cancer, and others do not, remains unclear. Current studies focus on genetic susceptibilities to lung cancer, and how they modify the effects of...
متن کاملMolecular Epidemiology of Lung Cancer Driver Mutations
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Abstract Purpose: The molecular epidemiology of most EGFR and KRAS mutations in lung cancer remains unclear. Experimental Design: We genotyped 3026 lung adenocarcinomas for the major EGFR (exon 19 deletions and L858R) and KRAS (G12, G13) mutations and examined correlations with demographic, cli...
متن کاملMolecular Epidemiology of Female Lung Cancer
Lung cancer is still a leading cause of cancer mortality in the world. The incidence of lung cancer in developed countries started to decrease mainly due to global anti-smoking campaigns. However, the incidence of lung cancer in women has been increasing in recent decades for various reasons. Furthermore, since the screening of lung cancer is not as yet very effective, clinically applicable mol...
متن کاملThe molecular epidemiology of lung cancer.
Lung cancer is the leading cause of cancer mortality worldwide. There have been only slight improvements in early diagnosis and survival, reflecting limited advances in screening and treatment for lung cancer. The identification of host differences in susceptibility to lung carcinogens, in particular to cigarette smoke, is essential in predicting who is at highest risk. Susceptibility differenc...
متن کاملThe Epidemiology of Lung Cancer in Lebanon During 2014
Background and aims: Lung cancer is the leading cause of cancer death worldwide. There are no recent data on the lung cancer prevalence in Lebanon, and the available data are based on prediction. Thus, this study aimed to determine the incidence rate of lung cancer during 2014, among patients who were newly diagnosed at Lebanese teaching hospitals. In addition, the study attempted to identify t...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 1999
ISSN: 0923-7534
DOI: 10.1093/annonc/10.suppl_5.s7